Why Invokana for DKD

 

Why Invokana for DKD

Mode of Action

How Invokana delivers renal benefits via urinary sodium

Invokana reduces glucose and sodium reabsorption, increases the amount of sodium reaching the macula densa, causing afferent arteriole constriction, reducing hyperfiltration and decreasing intraglomerular pressure1.

View mode of action video here:

This video elaborates the mechanism of action of Invokana.

References
  • 1. Invokana Summary of Product Characteristics. Napp Pharmaceuticals Limited. Available at: https://www.medicines.org.uk/emc/product/8855/smpc and https://www.medicines.org.uk/emc/product/12057/smpc [Accessed March 2021].