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Early Identification of Kidney Disease

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Prescribing Information

Great Britain Northern Ireland

The Importance of Early Identification

Why is it important to look for the early signs of diabetic kidney disease (DKD) in your patients with type 2 diabetes mellitus (T2DM)?

  • One of the earliest complications of T2DM is kidney decline1
  • If recognised early, kidney disease in diabetes can be effectively slowed down2
  • Early screening and using medications with proven effectiveness can reduce the burden of DKD2
  • 38% of patients with T2DM haven’t had a urine albumin check within the last year3

The role of ACR and eGFR as early markers of DKD

Importance of Early Identification
  • Whole-kidney GFR may remain normal even in the presence of considerable loss of nephron mass4
    • The graph indicates that by the time the estimated glomerular filtration rate (eGFR) falls below 60 mL/min/1.73 m2, the patient may have already lost 60-80% of their nephron mass4
  • By using ACR testing, early signs of DKD can be detected before significant nephron loss has occurred4

Using ACR and/or eGFR categories to assess a patients risk

  • 38% of patients with T2DM haven’t had a urine albumin check within the last year3
Risk of adverse renal and CV outcome

Professor David Wheeler explains the importance of early detection of DKD in people with T2DM

Abbreviations

ACR: Albumin Creatinine Ratio; DKD: Diabetic Kidney Disease; eGFR: estimated Glomerular Filtration Rate; T2DM: Type 2 Diabetes Mellitus.

References

Reporting adverse events

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard.

Adverse events should also be reported to Napp Pharmaceuticals Limited on 01223 424444 or drugsafetyuk@napp.co.uk.